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Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn

Published in Plant (Volume 5, Issue 4)
Received: 7 March 2017     Accepted: 27 March 2017     Published: 30 October 2017
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Abstract

Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.

Published in Plant (Volume 5, Issue 4)
DOI 10.11648/j.plant.20170504.12
Page(s) 68-72
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Glycyrrhiza Glabra Linn, Orgnic Extracts, Antioxidant, Antibacterials

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Cite This Article
  • APA Style

    Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, et al. (2017). Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant, 5(4), 68-72. https://doi.org/10.11648/j.plant.20170504.12

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    ACS Style

    Zafar Iqbal; Zhang Hai; Hong Yan Ping; Abdul Ghaffar; Munaza Mumtaz, et al. Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant. 2017, 5(4), 68-72. doi: 10.11648/j.plant.20170504.12

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    AMA Style

    Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, et al. Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant. 2017;5(4):68-72. doi: 10.11648/j.plant.20170504.12

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  • @article{10.11648/j.plant.20170504.12,
      author = {Zafar Iqbal and Zhang Hai and Hong Yan Ping and Abdul Ghaffar and Munaza Mumtaz and Luban Liaqat},
      title = {Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn},
      journal = {Plant},
      volume = {5},
      number = {4},
      pages = {68-72},
      doi = {10.11648/j.plant.20170504.12},
      url = {https://doi.org/10.11648/j.plant.20170504.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.20170504.12},
      abstract = {Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn
    AU  - Zafar Iqbal
    AU  - Zhang Hai
    AU  - Hong Yan Ping
    AU  - Abdul Ghaffar
    AU  - Munaza Mumtaz
    AU  - Luban Liaqat
    Y1  - 2017/10/30
    PY  - 2017
    N1  - https://doi.org/10.11648/j.plant.20170504.12
    DO  - 10.11648/j.plant.20170504.12
    T2  - Plant
    JF  - Plant
    JO  - Plant
    SP  - 68
    EP  - 72
    PB  - Science Publishing Group
    SN  - 2331-0677
    UR  - https://doi.org/10.11648/j.plant.20170504.12
    AB  - Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.
    VL  - 5
    IS  - 4
    ER  - 

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Author Information
  • Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan

  • School of Chemistry and Chemical Engineering, Qianbei Featured Resources, Applied Research Key Laboratory, Zunyi Normal College, Guizhou, Zunyi, China

  • Jiangxi Key Laboratory of Natural Product and Functional Food, College of Food Science and Engineering, Jiangxi, Agriculutural University, Nanchang, China

  • Department of Applied Chemistry, University of Engineering and Technology, Lahore, Pakistan

  • Department of Applied Chemistry, University of Engineering and Technology, Lahore, Pakistan

  • Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan

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